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Creutzig U, Harbott J, Sperling C, Ritter J, Zimmermann M, Lffler H, Riehm H, Schellong G, Ludwig WD. Reflex tests will be performed at an additional charge for each marker tested (FIRST if applicable, ADD1 if applicable). 2013 Jan;92(1):89-96. doi: 10.1007/s00277-012-1574-3. Would you like email updates of new search results? Am J Med. Accessibility FOIA Overall, del(13q14) and +12 were the most common abnormalities (39%), whereas del(11q13), del(17p13), and del(6q23) were detected only in 3, 1, and 0 cases, respectively. Application of these criteria to a series of nearly 500 cases of lymphoma indicated that over 90% of B-lineage and about 80% of T-lineage neoplasms manifested immunophenotypic abnormalities that could distinguish them from benign, reactive lymphoid processes. Kruglov O, Johnson LDS, Minic A, Jordan K, Uger RA, Wong M, Sievers EL, Shou Y, Akilov OE. Please enable it to take advantage of the complete set of features! Immunophenotypic criteria for the diagnosis of non-Hodgkin's - PubMed With the exception of the MB2 B-cell-associated antigen, no B- and T-cell differentiation antigen was detected in case 1. Shi M, Jevremovic D, Otteson GE, Timm MM, Olteanu H, Horna P: Single antibody detection of T-cell receptor alpha beta clonality by flow cytometry rapidly identifies mature T-cell neoplasms and monotypic small CD8-positive subsets of uncertain significance. This technique helps identify the lineage. Search by expertise, name or affiliation. Immunophenotyping - an overview | ScienceDirect Topics low reading R03.1 . In these cases, LSC analysis is a methodology of choice because of its low sample requirements. Morphologic evaluation and flow cytometric immunophenotypic analysis revealed no evidence of plasma cell neoplasm involving the BM. 1985 May;134(5):2995-3002 3. MedlinePlus Medical Encyclopedia [On-line information]. Available online at https://www.lls.org/managing-your-cancer/lab-and-imaging-tests/blood-tests#Immunophenotyping. Accessed December 2014. -T-cell receptor gene rearrangement to examine clonality of T cells in cases showing phenotypically aberrant T-cell population.