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0000018201 00000 n McHugh et al., Science Translational Medicine (2019), Smartphone images of the quantum dot markings in the skin of rodents at 0 weeks and 12 weeks after administration. 0000000016 00000 n 0000105025 00000 n In addition to the stand-alone value of an intradermal information encoding and detection platform, this system may offer greater advantages when co-delivered with vaccines, they stated. How would one create the LUCIFERASE enzyme in the body? Along with the vaccine, a child would be injected with a bit of dye that is invisible to the naked eye but easily seen with a special cell-phone filter, combined with an app that shines near-infrared light onto the skin. Researchers develop microneedle patch for flu vaccination Add that onto the backlash that already comes part and parcel with vaccines on the whole, and the situation could compound hesitancy and misinformation, she says. By conjugating luciferase protein to quantum dots, bio-luminescence resonance energy transfer Its possible someday that this invisible approach could create new possibilities for data storage, biosensing, and vaccine applications that could improve how medical care is provided, particularly in the developing world, said senior researcher Robert Langer, PhD, the David H. Koch Institute professor at MIT. Potential patients could reject the procedure out of fear or mistrust, worrying, for instance, that authorities are using the patches to encrypt information onto individuals. 0000009589 00000 n Fig. This, I think, is a pretty interesting way to accomplish those goals.. Not Just Ventilators: Staff Trained to Run Them Are in Short Supply, Coronavirus Vaccines May Not Work for the Elderly--and This Lab Aims to Change That, "Fake News" Web Sites May Not Have a Major Effect on Elections. Fig. Fig. 0000027694 00000 n They are also exploring ways to exploit modulation of the BRET signal to detect enzyme or protein function.