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Healthcare professionals should use caution when conducting exercise capacity testing with some patients, especially those withpost-exertional malaise(i.e., the worsening of symptoms following even minor physical or mental exertion, with symptoms typically worsening 12 to 48 hours after activity and lasting for days or even weeks). 2019 Jun;15(2):98-101. doi:10.1183/20734735.0013-2019, Lavery AM, Preston LE, Ko JY, et al. Lambert N, Survivor Corps, El-Azab SA, et al. The current hypothesis is that these lesions are a result of the inflammation caused by the virus itself, along with the consequences of mechanical ventilation in patients who require intubation. For information about antibody testing, see Using Antibody Tests for COVID-19. This is what the research says. As the infection slowly moves across the lung, it leaves damage in its wake and continuously fuels the fever, low blood pressure and damage to the kidneys, brain, heart and other organs inpatients with COVID-19. Over the coming months, determining both the real incidence of after-effects and how to treat them is of high importance, in order to understand the full impact of pneumonia caused by COVID-19 in patients. We saw a higher risk of respiratory failure, dementia, and post-viral fatigue in the COVID-19 group, compared to the lower respiratory tract infection group, but the other sequelae did not occur with a higher frequency in the COVID-19 group.. This category is heterogeneous, as it can include patients who have clinically important but poorly understood symptoms (e.g., difficulty thinking or concentrating, post-exertional malaise) that can be persistent or intermittent after initial acute infection with SARS-CoV-2. 2021 Apr;27(4):601-615. doi:10.1038/s41591-021-01283-z, Policy Brief 39 In the Wake of the Pandemic Preparing for Long COVID. Accessed at: https://www.nice.org.uk/guidance/NG188, Sis-Almirall A, Brito-Zern P, Conangla Ferrn L, et al. Sequelae in Adults at 6 Months After COVID-19 Infection. Ir J Med Sci. This is not to say that people shouldnt get vaccinated I just think that were still early in this process and that its important to look at the long-term effects of anything that were doing in medicine, said Dr. Arbaje.